Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets
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چکیده
منابع مشابه
Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets.
Inflammatory bowel disease reflects an aberrant mucosal CD4+ T cell response to commensal enteric bacteria. In addition to regulatory T cell subsets, recent studies have revealed a protective role of B cells in murine CD4+ T cell colitis, but the relationship of their action to T cell immunoregulation is unknown. Here we report that mesenteric lymph node (MLN) B cells protect mice from colitis ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2005
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0409449102